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ZIRC
ZFIN ID: ZDB-GENE-060315-7
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Gene Name: Rho family GTPase 1b
Gene Symbol: rnd1b    Nomenclature History

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Previous Names: Rnd1a (1), rnd1l, wu:fk50c04, zgc:153089

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including Rho protein signal transduction; actin cytoskeleton organization; and regulation of cell shape. Predicted to colocalize with the plasma membrane. Is expressed in several structures, including blastomere; germ ring; margin; optic primordium; and presumptive mesoderm. Orthologous to human RND1 (Rho family GTPase 1).
Genome Resources: Alliance (1),  Gene:553414 (1),  Ensembl(GRCz11):ENSDARG00000004218 (1)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa43993 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rnd1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rnd1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process small GTPase mediated signal transduction (more)
    Cellular Component cell cortex (more)
    Molecular Function GTPase activity (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001806 (1)
  • InterPro:IPR003578 (1)
  • InterPro:IPR005225 (1)
  • InterPro:IPR027417 (1)
  • PROSITE:PS51420 (1)
  • Pfam:PF00071 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript rnd1b-202 (1)    Ensembl 1034
    Select Tool
    mRNA rnd1b-201 (1)    Ensembl 3054
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    Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rnd1b No data available
    MARKER RELATIONSHIPS
    rnd1b Contained in: [BAC] CH73-339C6 (1) (order this), CH73-355C8 (1) (order this)
    rnd1b Encodes: [EST] fk50c04
    [cDNA] MGC:153089 (1) (order this), MGC:192330 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001044396 (1) 985 bp
    Select Tool
    Genomic GenBank:CT573349 (1) 89200 bp
    Select Tool
    Polypeptide UniProtKB:Q52WX7 (1) 232 aa
    Select Tool
    Sequence Clusters UniGene:159775 (1)
    Sequence Information (all 22)
    ORTHOLOGY for rnd1b ( Chr: 23 )
    CITATIONS (21)