Gene

slc6a4b

ID
ZDB-GENE-060314-2
Name
solute carrier family 6 member 4b
Symbol
slc6a4b Nomenclature History
Previous Names
  • sertb (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have serotonin binding activity and serotonin:sodium symporter activity. Predicted to be involved in serotonin uptake. Predicted to localize to neuron projection and plasma membrane. Is expressed in nervous system. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; anxiety disorder (multiple); autistic disorder; heart disease (multiple); and obstructive sleep apnea. Orthologous to human SLC6A4 (solute carrier family 6 member 4).
Genome Resources
Note
None
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc6a4b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
anxiety disorder Alliance {Anxiety-related personality traits} 607834
{Obsessive-compulsive disorder} 164230
Associated With slc6a4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000175 Sodium:neurotransmitter symporter
Homologous_superfamily IPR037272 Sodium:neurotransmitter symporter superfamily
Domain Details Per Protein
Protein Length Sodium:neurotransmitter symporter Sodium:neurotransmitter symporter superfamily
UniProtKB:B3DJ31 591
UniProtKB:Q1WGB4 361
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations