Gene

cdc42l2

ID
ZDB-GENE-060312-21
Name
cell division cycle 42 like 2
Symbol
cdc42l2 Nomenclature History
Previous Names
  • cdc42b (1)
  • zgc:136923
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Is predicted to enable GTP binding activity and GTPase activity. Involved in several processes, including Cdc42 protein signal transduction; cell projection assembly; and endocytosis. Acts upstream of or within cell cycle; cell division; and small GTPase mediated signal transduction. Human ortholog(s) of this gene implicated in fibrosarcoma. Orthologous to human CDC42 (cell division cycle 42).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Tay et al., 2010
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdc42l2 Human Ortholog
No data available
Associated With cdc42l2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005225 Small GTP-binding protein domain
Family IPR001806 Small GTPase
Family IPR003578 Small GTPase Rho
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length P-loop containing nucleoside triphosphate hydrolase Small GTPase Small GTPase Rho Small GTP-binding protein domain
UniProtKB:Q29RA1 185
UniProtKB:A3QJU6 209
UniProtKB:A0A2R8QSF7 185
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations