Gene

kcnj8

ID
ZDB-GENE-060308-1
Name
potassium inwardly rectifying channel subfamily J member 8
Symbol
kcnj8 Nomenclature History
Previous Names
  • Kir6.1 (1)
  • si:dkey-183c2.2
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have ATP-activated inward rectifier potassium channel activity. Predicted to be involved in potassium ion import across plasma membrane and regulation of ion transmembrane transport. Predicted to localize to plasma membrane. Used to study hypertrichotic osteochondrodysplasia Cantu type. Orthologous to human KCNJ8 (potassium inwardly rectifying channel subfamily J member 8).
Genome Resources
Note
None
Expression
All Expression Data
Fig. 3 from Emfinger et al., 2017
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Tessadori et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kcnj8 Human Ortholog
No data available
Associated With kcnj8 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR040445 Potassium channel, inwardly rectifying, transmembrane domain
Domain IPR041647 Inward rectifier potassium channel, C-terminal
Family IPR003278 Potassium channel, inwardly rectifying, Kir6.1
Family IPR016449 Potassium channel, inwardly rectifying, Kir
Homologous_superfamily IPR013518 Potassium channel, inwardly rectifying, Kir, cytoplasmic
Homologous_superfamily IPR014756 Immunoglobulin E-set
Domain Details Per Protein
Protein Length Immunoglobulin E-set Inward rectifier potassium channel, C-terminal Potassium channel, inwardly rectifying, Kir Potassium channel, inwardly rectifying, Kir6.1 Potassium channel, inwardly rectifying, Kir, cytoplasmic Potassium channel, inwardly rectifying, transmembrane domain
UniProtKB:Q5RH88 416
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations