Gene
cnksr2a
- ID
- ZDB-GENE-060228-5
- Name
- connector enhancer of kinase suppressor of Ras 2a
- Symbol
- cnksr2a Nomenclature History
- Previous Names
-
- cnksr2
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to be involved in regulation of signal transduction. Predicted to localize to cytoplasm and membrane. Human ortholog(s) of this gene implicated in syndromic X-linked mental retardation Hough type. Orthologous to human CNKSR2 (connector enhancer of kinase suppressor of Ras 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| syndromic X-linked mental retardation Hough type | Alliance | Intellectual developmental disorder, X-linked syndromic, Houge type | 301008 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001478 | PDZ domain |
| Domain | IPR001660 | Sterile alpha motif domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR010599 | Connector enhancer of kinase suppressor of ras 2/3 domain |
| Domain | IPR017874 | CRIC domain |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR013761 | Sterile alpha motif/pointed domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
| Protein | Length | Connector enhancer of kinase suppressor of ras 2/3 domain | CRIC domain | PDZ domain | PDZ superfamily | PH-like domain superfamily | Pleckstrin homology domain | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B6Q4
|
1032 | ||||||||
|
UniProtKB:A0A8M3AZ62
|
1024 | ||||||||
|
UniProtKB:A0A8M6Z4T4
|
1031 | ||||||||
|
UniProtKB:A0A8M3AW25
|
975 | ||||||||
|
UniProtKB:A0A8M9PXZ0
|
1034 | ||||||||
|
UniProtKB:A0A8M9PUH1
|
976 | ||||||||
|
UniProtKB:A0A8M3APA0
|
1025 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
cnksr2a-202
(1)
|
Havana | 2050 nt |
Interactions and Pathways
No data available
Plasmids
No data available