Gene
corin
- ID
- ZDB-GENE-060224-3
- Name
- corin, serine peptidase
- Symbol
- corin Nomenclature History
- Previous Names
-
- si:ch1073-76a20.1
- zmp:0000000798
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable scavenger receptor activity and serine-type endopeptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in hypertension and pre-eclampsia. Orthologous to human CORIN (corin, serine peptidase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR033116 | Serine proteases, trypsin family, serine active site |
| Conserved_site | IPR023415 | Low-density lipoprotein (LDL) receptor class A, conserved site |
| Domain | IPR001190 | SRCR domain |
| Domain | IPR001254 | Serine proteases, trypsin domain |
| Domain | IPR020067 | Frizzled domain |
| Domain | IPR041762 | Corin, cysteine-rich domain 1 |
| Domain | IPR041763 | Corin, cysteine-rich domain 2 |
| Family | IPR050685 | Low-density lipoprotein receptor |
| Homologous_superfamily | IPR009003 | Peptidase S1, PA clan |
| Homologous_superfamily | IPR036055 | LDL receptor-like superfamily |
| Homologous_superfamily | IPR036772 | SRCR-like domain superfamily |
| Homologous_superfamily | IPR036790 | Frizzled cysteine-rich domain superfamily |
| Homologous_superfamily | IPR043504 | Peptidase S1, PA clan, chymotrypsin-like fold |
| Repeat | IPR002172 | Low-density lipoprotein (LDL) receptor class A repeat |
Domain Details Per Protein
| Protein | Length | Corin, cysteine-rich domain 1 | Corin, cysteine-rich domain 2 | Frizzled cysteine-rich domain superfamily | Frizzled domain | LDL receptor-like superfamily | Low-density lipoprotein (LDL) receptor class A, conserved site | Low-density lipoprotein (LDL) receptor class A repeat | Low-density lipoprotein receptor | Peptidase S1, PA clan | Peptidase S1, PA clan, chymotrypsin-like fold | Serine proteases, trypsin domain | Serine proteases, trypsin family, serine active site | SRCR domain | SRCR-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AP01
|
1036 | ||||||||||||||
|
UniProtKB:A0A8M6YVI3
|
723 |
Interactions and Pathways
No data available
Plasmids
No data available