Gene

zfpm2b

ID
ZDB-GENE-060130-5
Name
zinc finger protein, FOG family member 2b
Symbol
zfpm2b Nomenclature History
Previous Names
  • fog2b (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable DNA binding activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and metal ion binding activity. Predicted to be involved in cell differentiation; heart development; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in anterior lateral plate mesoderm; central nervous system; midbrain; and posterior lateral plate mesoderm. Human ortholog(s) of this gene implicated in 46,XY sex reversal 9; myelodysplastic syndrome; and tetralogy of Fallot. Orthologous to human ZFPM2 (zinc finger protein, FOG family member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With zfpm2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
46,XY sex reversal 9 Alliance 46XY sex reversal 9 616067
congenital diaphragmatic hernia Alliance Diaphragmatic hernia 3 610187
tetralogy of Fallot Alliance Tetralogy of Fallot 187500
Associated With zfpm2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Domain IPR034731 Zinc finger CCHC FOG-type
Family IPR039746 FOG family
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length FOG family Zinc finger C2H2 superfamily Zinc finger C2H2-type Zinc finger CCHC FOG-type
UniProtKB:Q2QKJ8 1093
UniProtKB:A0A0R4IQP3 1093
UniProtKB:B2GM63 1018
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations