Gene
zfpm2a
- ID
- ZDB-GENE-060130-4
- Name
- zinc finger protein, FOG family member 2a
- Symbol
- zfpm2a Nomenclature History
- Previous Names
-
- fog2a (1)
- zgc:152696
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have RNA polymerase II transcription factor binding activity. Predicted to be involved in cell differentiation; heart development; and negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in 46,XY sex reversal 9; myelodysplastic syndrome; and tetralogy of Fallot. Is expressed in midbrain. Orthologous to human ZFPM2 (zinc finger protein, FOG family member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Walton et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| 46,XY sex reversal 9 | Alliance | 46XY sex reversal 9 | 616067 |
| congenital diaphragmatic hernia | Alliance | Diaphragmatic hernia 3 | 610187 |
| tetralogy of Fallot | Alliance | Tetralogy of Fallot | 187500 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013087 | Zinc finger C2H2-type |
| Domain | IPR034731 | Zinc finger CCHC FOG-type |
| Domain | IPR049361 | Zinc finger protein ZFPM1/2, PR domain |
| Family | IPR039746 | FOG family |
| Homologous_superfamily | IPR036236 | Zinc finger C2H2 superfamily |
| Homologous_superfamily | IPR046341 | SET domain superfamily |
Domain Details Per Protein
| Protein | Length | FOG family | SET domain superfamily | Zinc finger C2H2 superfamily | Zinc finger C2H2-type | Zinc finger CCHC FOG-type | Zinc finger protein ZFPM1/2, PR domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q2QKJ9
|
1141 | ||||||
|
UniProtKB:F1R4T3
|
1142 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zfpm2a-201
(1)
|
Ensembl | 4,564 nt | ||
| mRNA |
zfpm2a-202
(1)
|
Ensembl | 1,126 nt | ||
| mRNA |
zfpm2a-203
(1)
|
Ensembl | 4,142 nt | ||
| mRNA |
zfpm2a-204
(1)
|
Ensembl | 402 nt | ||
| mRNA |
zfpm2a-205
(1)
|
Ensembl | 4,007 nt |
Interactions and Pathways
No data available
Plasmids
No data available