Community Action Needed: Please respond to the NIH RFI
Gene

crybb3

ID
ZDB-GENE-060130-2
Name
crystallin, beta B3
Symbol
crybb3 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to be a structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Is expressed in eye and lens. Human ortholog(s) of this gene implicated in cataract 22 multiple types. Orthologous to human CRYBB3 (crystallin beta B3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With crybb3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cataract 22 multiple types Alliance Cataract 22 609741
Associated With crybb3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001064 Beta/gamma crystallin
Family IPR033115 Beta-crystallin B3
Homologous_superfamily IPR011024 Gamma-crystallin-like
Domain Details Per Protein
Protein Length Beta-crystallin B3 Beta/gamma crystallin Gamma-crystallin-like
UniProtKB:Q52JI3 259
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations