Gene

slc8a1b

ID

ZDB-GENE-060110-3

Name

solute carrier family 8 member 1b

Symbol

slc8a1b Nomenclature History

Previous Names

ncx1b (1)
ncx1n (1)

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have calcium:sodium antiporter activity. Predicted to be involved in calcium ion transport; cell communication; and transmembrane transport. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in hypertension. Is expressed in several structures, including blood; eye; liver; neural tube; and pleuroperitoneal region. Orthologous to human SLC8A1 (solute carrier family 8 member A1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

16 figures from 10 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc8a1b Human Ortholog

No data available

Associated With slc8a1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001623	DnaJ domain
Domain	IPR003644	Na-Ca exchanger/integrin-beta4
Domain	IPR004837	Sodium/calcium exchanger membrane region
Domain	IPR032452	Sodium/calcium exchanger domain, C-terminal extension
Family	IPR004836	Sodium/calcium exchanger protein
Family	IPR051171	Calcium/Cation Antiporter
Homologous_superfamily	IPR038081	CalX-like domain superfamily
Homologous_superfamily	IPR044880	NCX, central ion-binding domain superfamily

Domain Details Per Protein

Protein	Length	Calcium/Cation Antiporter	CalX-like domain superfamily	DnaJ domain	Na-Ca exchanger/integrin-beta4	NCX, central ion-binding domain superfamily	Sodium/calcium exchanger domain, C-terminal extension	Sodium/calcium exchanger membrane region	Sodium/calcium exchanger protein
UniProtKB:B2CZC2 InterPro	942
UniProtKB:A0A8M9P932 InterPro	310
UniProtKB:Q32SG7 InterPro	944

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	slc8a1b-201 (1) Ensembl	Ensembl	2,835 nt	Select Tool
mRNA	slc8a1b-202 (1) Ensembl	Ensembl	4,238 nt	Select Tool
mRNA	slc8a1b-203 (1) Ensembl	Ensembl	2,955 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations