Gene
irge4
- ID
- ZDB-GENE-051212-2
- Name
- immunity-related GTPase family, e4
- Symbol
- irge4 Nomenclature History
- Previous Names
-
- zgc:158767
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity and GTPase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in inflammatory bowel disease 19 and tuberculosis. Orthologous to human IRGM (immunity related GTPase M).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Sieger et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Immunity-related GTPase | Immunity-related GTPases-like | IRG-type guanine nucleotide-binding (G) domain | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9P7N2
|
772 | ||||
|
UniProtKB:A2RV34
|
385 |
Interactions and Pathways
No data available
Plasmids
No data available