Gene

pstpip1b

ID
ZDB-GENE-051127-25
Name
proline-serine-threonine phosphatase interacting protein 1b
Symbol
pstpip1b Nomenclature History
Previous Names
  • zgc:123255
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity. Predicted to be involved in actin filament polymerization. Predicted to localize to actin filament; cytoplasm; and plasma membrane. Human ortholog(s) of this gene implicated in PAPA syndrome. Orthologous to human PSTPIP1 (proline-serine-threonine phosphatase interacting protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pstpip1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
PAPA syndrome Alliance Pyogenic sterile arthritis, pyoderma gangrenosum, and acne 604416
Autoinflammatory syndrome with cytopenia, hyperzincemia, and hypercalprotectinemia 601979
Associated With pstpip1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001060 FCH domain
Domain IPR001452 SH3 domain
Domain IPR030777 PSTPIP1, SH3 domain
Domain IPR031160 F-BAR domain
Homologous_superfamily IPR027267 AH/BAR domain superfamily
Homologous_superfamily IPR036028 SH3-like domain superfamily
Domain Details Per Protein
Protein Length AH/BAR domain superfamily F-BAR domain FCH domain PSTPIP1, SH3 domain SH3 domain SH3-like domain superfamily
UniProtKB:Q2YDR2 379
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations