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General Information
ZIRC
ZFIN ID: ZDB-GENE-051120-90
Gene Name: protoporphyrinogen oxidase
Gene Symbol: ppox
Sequence Ontology ID : SO:0000704

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Previous Names: ppo (1), mno (1), montalcino (1), zgc:123252

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have oxygen-dependent protoporphyrinogen oxidase activity; predicted to be involved in oxidation-reduction process and protoporphyrinogen IX biosynthetic process; predicted to localize  ...
GENE EXPRESSION
All Expression Data: 5 figures from 3 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6443 Point Mutation Unknown Splice Site ENU
t23572 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tia048 Point Mutation Unknown Unknown ENU
    Targeting reagents:
    DISEASE ASSOCIATED WITH ppox HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    variegate porphyria Porphyria variegata 176200
    DISEASE ASSOCIATED WITH ppox VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    variegate porphyria ppoxt23572/t23572(TU) standard conditions Dooley et al., 2008
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component mitochondrion (more)
    Molecular Function oxidoreductase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002937 (1)
  • InterPro:IPR004572 (1)
  • InterPro:IPR036188 (1)
  • Pfam:PF01593 (1)
  • EC:1.3.3.4 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ppox No data available
    MARKER RELATIONSHIPS
    ppoxEncodes: [cDNA] MGC:123252 (1) (order this), MGC:174614 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001039979 (1)
    Genomic GenBank:FO704709 (1) 40556bp
    Select Tool
    Polypeptide UniProtKB:A8KC40 (1) 477aa
    Sequence Clusters UniGene:87769 (1)
    Sequence Information (all 21)
    OTHER ppox GENE PAGES
  • Alliance (1)
  • Gene:664750 (1)
  • Ensembl(GRCz11):ENSDARG00000102167 (1)
  • ORTHOLOGY for ppox (Chr: 16)
    CITATIONS (26)