Gene
drd4-rs
- ID
- ZDB-GENE-051113-172
- Name
- dopamine receptor D4 related sequence
- Symbol
- drd4-rs Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have adrenergic receptor activity; dopamine binding activity; and dopamine neurotransmitter receptor activity, coupled via Gi/Go. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; behavioral response to cocaine; and regulation of ion transport. Predicted to localize to integral component of plasma membrane and synaptic vesicle membrane. Human ortholog(s) of this gene implicated in several diseases, including Gilles de la Tourette syndrome; antisocial personality disorder; attention deficit hyperactivity disorder; conduct disorder; and dyslexia. Is expressed in adenohypophyseal placode; central nervous system; otic vesicle; and pharyngeal arch 3-7 skeleton. Orthologous to human DRD4 (dopamine receptor D4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Dopamine D4 receptor | Dopamine receptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|
|
UniProtKB:Q32PM9
|
418 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
drd4-rs-201
(1)
|
Havana | 1716 nt |
Interactions and Pathways
No data available
Plasmids
No data available