Gene

ppifb

ID

ZDB-GENE-051030-126

Name

peptidylprolyl isomerase Fb

Symbol

ppifb Nomenclature History

Previous Names

im:7151275 (1)
zgc:123307 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have cyclosporin A binding activity; peptidyl-prolyl cis-trans isomerase activity; and unfolded protein binding activity. Predicted to be involved in cellular response to hydrogen peroxide; protein refolding; and regulation of mitochondrial membrane permeability involved in programmed necrotic cell death. Predicted to localize to mitochondrion. Orthologous to human PPIF (peptidylprolyl isomerase F).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7151275 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ppifb Human Ortholog

No data available

Associated With ppifb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020892	Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
Domain	IPR002130	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
Family	IPR024936	Cyclophilin-type peptidyl-prolyl cis-trans isomerase
Homologous_superfamily	IPR029000	Cyclophilin-like domain superfamily