ZFIN ID: ZDB-GENE-050913-114
Gene Name: macroH2A.2 histone
Gene Symbol: macroh2a2    Nomenclature History

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Previous Names: H2A2 (1), h2afy2, im:6898017, wu:fa14g05, zgc:114051

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Exhibits transcription regulatory region sequence-specific DNA binding activity. Involved in brain development. Predicted to localize to nuclear chromatin. Is expressed in brain; central nervous system; retina; and retinal ganglion cell layer. Orthologous to human MACROH2A2 (macroH2A.2 histone).
Genome Resources: Alliance (1),  Gene:558711 (1),  Ensembl(GRCz11):ENSDARG00000087897 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (8 images) from Thisse et al., 2004 [IMAGE:6898017]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-macroh2a2
2
MO1-macroh2a2 N/A 1
MO2-macroh2a2 N/A 1
DISEASE ASSOCIATED WITH macroh2a2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH macroh2a2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process brain development (more)
Cellular Component chromosome (more)
Molecular Function transcription regulatory region sequence-specific DNA binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA h2afy2-201 (1)    Ensembl 2001
h2afy2-202 (1)    Ensembl 678
h2afy2-203 (1)    Ensembl 897
h2afy2-204 (1)    Ensembl 883
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM macroh2a2 No data available
MARKER RELATIONSHIPS
macroh2a2 Contained in: [BAC] CH73-343M8 (1), DKEY-98E8 (1) (order this)
macroh2a2 Encodes: [EST] fa14g05, IMAGE:6898017 (1)
[cDNA] MGC:114051 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001025502 (1) 2011 nt
Genomic GenBank:CU929381 (1) 168054 nt
Select Tool
Polypeptide UniProtKB:Q4V914 (1) 367 aa
Sequence Information (all 17)
ORTHOLOGY for macroh2a2 ( Chr: 13 )
CITATIONS (28)