Gene
sla1a
- ID
- ZDB-GENE-050904-3
- Name
- Src like adaptor 1a
- Symbol
- sla1a Nomenclature History
- Previous Names
-
- sla1
- zgc:113360 (1)
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable epidermal growth factor receptor binding activity and phosphotyrosine residue binding activity. Predicted to be involved in regulation of MAPK cascade and signal transduction. Predicted to be part of COP9 signalosome. Predicted to be active in cytoplasm; nucleoplasm; and plasma membrane. Is expressed in macrophage. Orthologous to human SLA (Src like adaptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7152914 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000980 | SH2 domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR035052 | SLAP, SH2 domain |
| Domain | IPR035596 | Src-like-adapter, SH3 domain |
| Family | IPR043539 | Grb2-like |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR036860 | SH2 domain superfamily |
Domain Details Per Protein
| Protein | Length | Grb2-like | SH2 domain | SH2 domain superfamily | SH3 domain | SH3-like domain superfamily | SLAP, SH2 domain | Src-like-adapter, SH3 domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q3ZB94
|
271 |
Interactions and Pathways
No data available
Plasmids
No data available