Gene
slc8a1a
- ID
- ZDB-GENE-050809-1
- Name
- solute carrier family 8 member 1a
- Symbol
- slc8a1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Exhibits calcium:sodium antiporter activity. Involved in several processes, including calcium ion transport; cellular calcium ion homeostasis; and sarcomere organization. Predicted to localize to membrane. Is expressed in heart primordium and pericardial region. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human SLC8A1 (solute carrier family 8 member A1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 20 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR003644 | Na-Ca exchanger/integrin-beta4 |
Domain | IPR004837 | Sodium/calcium exchanger membrane region |
Domain | IPR032452 | Sodium/calcium exchanger domain, C-terminal extension |
Family | IPR004836 | Sodium/calcium exchanger protein |
Homologous_superfamily | IPR038081 | CalX-like domain superfamily |
Homologous_superfamily | IPR044880 | NCX, central ion-binding domain superfamily |
Domain Details Per Protein
Protein | Length | CalX-like domain superfamily | Na-Ca exchanger/integrin-beta4 | NCX, central ion-binding domain superfamily | Sodium/calcium exchanger domain, C-terminal extension | Sodium/calcium exchanger membrane region | Sodium/calcium exchanger protein |
---|---|---|---|---|---|---|---|
UniProtKB:Q1JQ21
|
693 | ||||||
UniProtKB:Q2TDX0
|
969 | ||||||
UniProtKB:F1R4F4
|
969 | ||||||
UniProtKB:A0A286YBI0
|
933 | ||||||
UniProtKB:Q501W6
|
696 | ||||||
UniProtKB:F6PC65
|
932 | ||||||
UniProtKB:Q32SG8
|
974 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
slc8a1a-202
(1)
|
3647 nt |
Interactions and Pathways
No data available
Plasmids
No data available