Gene

hamp

ID
ZDB-GENE-050726-1
Name
hepcidin antimicrobial peptide
Symbol
hamp Nomenclature History
Previous Names
  • hamp1
  • hamp2
  • hep (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Exhibits lipopolysaccharide binding activity; lipoteichoic acid binding activity; and peptidoglycan binding activity. Involved in cellular response to progesterone stimulus; defense response to bacterium; and iron ion homeostasis. Predicted to localize to extracellular region. Is expressed in blood plasma; gut; head kidney; intestine; and liver. Human ortholog(s) of this gene implicated in anemia; hemochromatosis; hemochromatosis type 2B; and hepatocellular carcinoma. Orthologous to human HAMP (hepcidin antimicrobial peptide).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
26 figures from 14 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Jiang et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hamp Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hemochromatosis type 2B Alliance Hemochromatosis, type 2B 613313
Associated With hamp Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR010500 Hepcidin
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations