Gene
atf7a
- ID
- ZDB-GENE-050721-2
- Name
- activating transcription factor 7a
- Symbol
- atf7a Nomenclature History
- Previous Names
-
- zgc:136234
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and cAMP response element binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in axial chorda mesoderm; notochord; and telencephalon. Orthologous to human ATF7 (activating transcription factor 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004827 | Basic-leucine zipper domain |
| Domain | IPR013087 | Zinc finger C2H2-type |
| Family | IPR016378 | Transcription factor cyclic AMP-dependent, CRE-BP1-type |
| Family | IPR051027 | Basic leucine zipper (bZIP) transcription factors |
| Homologous_superfamily | IPR036236 | Zinc finger C2H2 superfamily |
1 - 5 of 6 Show all
Domain Details Per Protein
| Protein | Additional Resources | Length | Basic leucine zipper (bZIP) transcription factors | Basic-leucine zipper domain | Basic-leucine zipper domain superfamily | Transcription factor cyclic AMP-dependent, CRE-BP1-type | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q4VGW9 | InterPro | 497 |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-136C12 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-9P24 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:136234 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:194836 | ZFIN Curated Data |
1 - 4 of 4
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001030205 (1) | 2423 nt | ||
| Genomic | GenBank:CR376824 (1) | 235026 nt | ||
| Polypeptide | UniProtKB:Q4VGW9 (1) | 497 aa |
- Dong, Z., Li, Y., Chen, X., Lai, X., Liu, M. (2020) A comparative study of the expression patterns of Fign family members in zebrafish embryonic development. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 251:110522
- Samarut, E., Bekri, A., Drapeau, P. (2016) Transcriptomic Analysis of Purified Embryonic Neural Stem Cells from Zebrafish Embryos Reveals Signaling Pathways Involved in Glycine-Dependent Neurogenesis. Frontiers in molecular neuroscience. 9:22
- Diotel, N., Viales, R.R., Armant, O., März, M., Ferg, M., Rastegar, S., Strähle, U. (2015) Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. The Journal of comparative neurology. 523(8):1202-21
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Zhao, C., Qi, J., and Meng, A. (2005) Characterization and expression pattern of two zebrafish atf7 genes. Developmental Dynamics : an official publication of the American Association of Anatomists. 233(3):1157-1162
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
1 - 6 of 6
Show