Gene

u2af2a

ID

ZDB-GENE-050706-131

Name

U2 small nuclear RNA auxiliary factor 2a

Symbol

u2af2a Nomenclature History

Previous Names

zgc:110115

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have poly-pyrimidine tract binding activity and pre-mRNA 3'-splice site binding activity. Predicted to be involved in RNA splicing; female sex differentiation; and mRNA processing. Predicted to localize to nucleus. Orthologous to human U2AF2 (U2 small nuclear RNA auxiliary factor 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With u2af2a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
developmental delay, dysmorphic facies, and brain anomalies	Alliance	Developmental delay, dysmorphic facies, and brain anomalies	620535

Associated With u2af2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Family	IPR006529	U2 snRNP auxilliary factor, large subunit, splicing factor
Family	IPR010519	Female-specific protein transformer
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily