Gene
mib2
- ID
- ZDB-GENE-050628-1
- Name
- MIB E3 ubiquitin protein ligase 2
- Symbol
- mib2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Exhibits identical protein binding activity. Contributes to ubiquitin-protein transferase activity. Involved in several processes, including melanocyte differentiation; protein autoubiquitination; and regulation of receptor internalization. Localizes to cytoplasmic vesicle and perinuclear region of cytoplasm. Is expressed in inner ear; mesenchyme pectoral fin; and pectoral fin. Orthologous to human MIB2 (mindbomb E3 ubiquitin protein ligase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Mikami et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000433 | Zinc finger, ZZ-type |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR010606 | Mib-herc2 |
| Domain | IPR040847 | Mind bomb, SH3 repeat domain |
| Domain | IPR042056 | E3 ubiquitin-protein ligase MIB1/2, zinc finger, ZZ-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Homologous_superfamily | IPR037252 | Mib/herc2 domain superfamily |
| Homologous_superfamily | IPR043145 | Zinc finger, ZZ-type superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | E3 ubiquitin-protein ligase MIB1/2, zinc finger, ZZ-type | Mib-herc2 | Mib/herc2 domain superfamily | Mind bomb, SH3 repeat domain | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, ZZ-type | Zinc finger, ZZ-type superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0AR23
|
999 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available