Gene

gstp1.1

ID

ZDB-GENE-050601-1

Name

glutathione S-transferase pi 1.1

Symbol

gstp1.1 Nomenclature History

Previous Names

gstp2 (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Enables glutathione transferase activity. Acts upstream of or within response to toxic substance. Predicted to be located in mitochondrion and nucleus. Predicted to be active in cytosol. Is expressed in brain; gill; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); carcinoma (multiple); hematologic cancer (multiple); reproductive organ cancer (multiple); and respiratory system disease (multiple). Orthologous to human GSTP1 (glutathione S-transferase pi 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 9 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gstp1.1 Human Ortholog

No data available

Associated With gstp1.1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004045	Glutathione S-transferase, N-terminal
Domain	IPR004046	Glutathione S-transferase, C-terminal
Domain	IPR010987	Glutathione S-transferase, C-terminal-like
Family	IPR003082	Glutathione S-transferase, Pi class
Family	IPR050213	Glutathione S-transferase superfamily
Homologous_superfamily	IPR036249	Thioredoxin-like superfamily
Homologous_superfamily	IPR036282	Glutathione S-transferase, C-terminal domain superfamily