Gene

arhgef3l

ID

ZDB-GENE-050522-85

Name

Rho guanine nucleotide exchange factor (GEF) 3, like

Symbol

arhgef3l Nomenclature History

Previous Names

zgc:109904 (1)

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in positive regulation of Rho protein signal transduction. Predicted to act upstream of or within intracellular signal transduction. Predicted to be located in cytoplasm.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:109904 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arhgef3l Human Ortholog

No data available

Associated With arhgef3l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR001331	Guanine-nucleotide dissociation stimulator, CDC24, conserved site
Domain	IPR000219	Dbl homology (DH) domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR044129	Rho guanine nucleotide exchange factor 3, PH domain
Family	IPR051480	Endocytic & GEF Adapter
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR035899	Dbl homology (DH) domain superfamily