capn2b

ID

ZDB-GENE-050522-84

Name

calpain 2, (m/II) large subunit b

Symbol

capn2b Nomenclature History

Previous Names

im:6908877
zgc:109906

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including digestive system; germ ring; hatching gland; periderm; and polster. Orthologous to human CAPN2 (calpain 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

17 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:109906 (13 images)
IMAGE:6908877 (7 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With capn2b Human Ortholog

No data available

Associated With capn2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR000169	Cysteine peptidase, cysteine active site
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR001300	Peptidase C2, calpain, catalytic domain
Domain	IPR002048	EF-hand domain
Domain	IPR022682	Peptidase C2, calpain, large subunit, domain III
Domain	IPR022683	Peptidase C2, calpain, domain III
Domain	IPR033883	Calpain subdomain III
Family	IPR022684	Peptidase C2, calpain family
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR036213	Calpain large subunit, domain III superfamily
Homologous_superfamily	IPR038765	Papain-like cysteine peptidase superfamily