Gene
impa2
- ID
- ZDB-GENE-050522-349
- Name
- inositol monophosphatase 2
- Symbol
- impa2 Nomenclature History
- Previous Names
-
- zgc:110201
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have inositol monophosphate 1-phosphatase activity. Predicted to be involved in inositol metabolic process; inositol phosphate dephosphorylation; and signal transduction. Human ortholog(s) of this gene implicated in bipolar disorder and schizophrenia. Is expressed in brain; central nervous system; epiphysis; optic vesicle; and retina. Orthologous to human IMPA2 (inositol monophosphatase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110201 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Stratman et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR020583 | Inositol monophosphatase, metal-binding site |
| Conserved_site | IPR020550 | Inositol monophosphatase, conserved site |
| Family | IPR000760 | Inositol monophosphatase-like |
| Family | IPR020552 | Inositol monophosphatase, lithium-sensitive |
| Family | IPR033942 | Inositol monophosphatase |
Domain Details Per Protein
| Protein | Length | Inositol monophosphatase | Inositol monophosphatase, conserved site | Inositol monophosphatase-like | Inositol monophosphatase, lithium-sensitive | Inositol monophosphatase, metal-binding site |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9P5W4
|
220 | |||||
|
UniProtKB:Q503S9
|
275 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available