Gene

cnot6l

ID

ZDB-GENE-050522-302

Name

CCR4-NOT transcription complex, subunit 6-like

Symbol

cnot6l Nomenclature History

Previous Names

zgc:111987

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have poly(A)-specific ribonuclease activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to localize to CCR4-NOT complex; cytoplasm; and nucleus. Orthologous to human CNOT6L (CCR4-NOT transcription complex subunit 6 like).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cnot6l Human Ortholog

No data available

Associated With cnot6l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR005135	Endonuclease/exonuclease/phosphatase
Domain	IPR034967	CCR4-NOT transcription complex subunit 6-like
Family	IPR050410	CCR4/nocturin mRNA turnover and transcription
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Homologous_superfamily	IPR036691	Endonuclease/exonuclease/phosphatase superfamily
Repeat	IPR001611	Leucine-rich repeat
Repeat	IPR003591	Leucine-rich repeat, typical subtype

Domain Details Per Protein

Protein	Length	CCR4/nocturin mRNA turnover and transcription	CCR4-NOT transcription complex subunit 6-like	Endonuclease/exonuclease/phosphatase	Endonuclease/exonuclease/phosphatase superfamily	Leucine-rich repeat	Leucine-rich repeat domain superfamily	Leucine-rich repeat, typical subtype
UniProtKB:A0A8M9PXK1 InterPro	549
UniProtKB:A2BHJ4 InterPro	559
UniProtKB:A0A8M9Q3B1 InterPro	407
UniProtKB:B2GPA8 InterPro	559

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	cnot6l-201 (1) Ensembl	Ensembl	2,613 nt	Select Tool ZFIN BLAST
mRNA	cnot6l-203 (1) Ensembl	Ensembl	1,681 nt	Select Tool ZFIN BLAST
ncRNA	cnot6l-002 (1) Ensembl	Ensembl	594 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations