Gene
lrmda
- ID
- ZDB-GENE-050522-285
- Name
- leucine rich melanocyte differentiation associated
- Symbol
- lrmda Nomenclature History
- Previous Names
-
- c10orf11 (1)
- c13h10orf11
- si:ch211-39f22.1
- zgc:112463
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Involved in melanocyte differentiation. Acts upstream of or within pigmentation. Is expressed in cranium; mucus secreting cell; neural crest; neural plate; and trunk. Human ortholog(s) of this gene implicated in oculocutaneous albinism type VII. Orthologous to human LRMDA (leucine rich melanocyte differentiation associated).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:112463 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Gronskov et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la027392Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| la027393Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| sa12051 | Allele with one point mutation | Unknown | Premature Stop | ENU |
1 - 3 of 3
Show
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| MO1-lrmda | N/A | Gronskov et al., 2013 |
| MO2-lrmda | N/A | Gronskov et al., 2013 |
| MO3-lrmda | N/A | Gronskov et al., 2013 |
1 - 3 of 3
Show
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| oculocutaneous albinism type VII | Alliance | Albinism, oculocutaneous, type VII | 615179 |
1 - 1 of 1
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Leucine-rich melanocyte differentiation-associated protein | Leucine-rich repeat | Leucine-rich repeat domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:Q501Y0 | InterPro | 234 |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001020701 (1) | 1514 nt | ||
| Genomic | GenBank:BX323799 (2) | 188145 nt | ||
| Polypeptide | UniProtKB:Q501Y0 (1) | 234 aa |