Gene

lrmda

ID

ZDB-GENE-050522-285

Name

leucine rich melanocyte differentiation associated

Symbol

lrmda Nomenclature History

Previous Names

c10orf11 (1)
c13h10orf11
si:ch211-39f22.1
zgc:112463

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Involved in melanocyte differentiation. Human ortholog(s) of this gene implicated in oculocutaneous albinism type VII. Is expressed in cranium; mucus secreting cell; neural crest; neural plate; and trunk. Orthologous to human LRMDA (leucine rich melanocyte differentiation associated).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:112463 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Gronskov et al., 2013
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lrmda Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
oculocutaneous albinism type VII	Alliance	Albinism, oculocutaneous, type VII	615179

Associated With lrmda Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR043313	Leucine-rich melanocyte differentiation-associated protein
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Repeat	IPR001611	Leucine-rich repeat