Gene
mffb
- ID
- ZDB-GENE-050522-208
- Name
- mitochondrial fission factor b
- Symbol
- mffb Nomenclature History
- Previous Names
-
- im:5082098
- zgc:110130
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have protein homodimerization activity. Predicted to be involved in mitochondrial fission; positive regulation of mitochondrial fission; and positive regulation of protein targeting to membrane. Predicted to localize to peroxisome. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human MFF (mitochondrial fission factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:5082098 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| encephalopathy due to defective mitochondrial and peroxisomal fission 2 | Alliance | Encephalopathy due to defective mitochondrial and peroxisomal fission 2 | 617086 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Mff-like domain | Mff/Tango-11 |
|---|---|---|---|
|
UniProtKB:A0A8M2BIG1
|
286 | ||
|
UniProtKB:Q503U3
|
275 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zgc:110130-202
(1)
|
Ensembl | 1,554 nt | ||
| ncRNA |
zgc:110130-002
(1)
|
Ensembl | 790 nt |
Interactions and Pathways
No data available
Plasmids
No data available