Gene

nefma

ID
ZDB-GENE-050522-205
Name
neurofilament medium chain a
Symbol
nefma Nomenclature History
Previous Names
  • zgc:112359 (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have structural molecule activity. Predicted to be involved in neurofilament bundle assembly. Predicted to localize to neurofilament. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is expressed in basal plate midbrain region and nervous system. Orthologous to human NEFM (neurofilament medium).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nefma Human Ortholog
No data available
Associated With nefma Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018039 Intermediate filament protein, conserved site
Domain IPR006821 Intermediate filament head, DNA-binding domain
Domain IPR011098 G5 domain
Domain IPR039008 Intermediate filament, rod domain
Family IPR002957 Keratin, type I
Family IPR027697 Neurofilament medium polypeptide
Homologous_superfamily IPR042180 Intermediate filament, rod domain, coil 1B
Domain Details Per Protein
Protein Length G5 domain Intermediate filament head, DNA-binding domain Intermediate filament protein, conserved site Intermediate filament, rod domain Intermediate filament, rod domain, coil 1B Keratin, type I Neurofilament medium polypeptide
UniProtKB:Q502B1 464
UniProtKB:A9JRN9 849
UniProtKB:F1QCR7 849
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations