Gene
alkbh1
- ID
- ZDB-GENE-050522-196
- Name
- alkB homolog 1, histone H2A dioxygenase
- Symbol
- alkbh1 Nomenclature History
- Previous Names
-
- si:ch211-133l14.1
- zgc:112365
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable broad specificity oxidative DNA demethylase activity; ferrous iron binding activity; and oxidative RNA demethylase activity. Predicted to be involved in oxidative RNA demethylation. Predicted to act upstream of or within DNA repair. Predicted to be active in cytoplasm and nucleus. Orthologous to human ALKBH1 (alkB homolog 1, histone H2A dioxygenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR005123 | Oxoglutarate/iron-dependent dioxygenase domain |
| Domain | IPR027450 | Alpha-ketoglutarate-dependent dioxygenase AlkB-like |
| Family | IPR004574 | Alkylated DNA repair protein AlkB |
| Homologous_superfamily | IPR037151 | Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily |
Domain Details Per Protein
| Protein | Length | Alkylated DNA repair protein AlkB | Alpha-ketoglutarate-dependent dioxygenase AlkB-like | Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily | Oxoglutarate/iron-dependent dioxygenase domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B5M4
|
329 | ||||
|
UniProtKB:Q502A8
|
363 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
alkbh1-202
(1)
|
Ensembl | 1,032 nt | ||
| mRNA |
alkbh1-201
(1)
|
Ensembl | 1,214 nt |
Interactions and Pathways
No data available
Plasmids
No data available