Gene

pde6ga

ID
ZDB-GENE-050522-144
Name
phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog a
Symbol
pde6ga Nomenclature History
Previous Names
  • zgc:112320 (1)
  • zgc:153837
  • zgc:158528
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have 3',5'-cyclic-GMP phosphodiesterase activity and cGMP binding activity. Predicted to be involved in activation of MAPK activity; positive regulation of G protein-coupled receptor signaling pathway; and positive regulation of epidermal growth factor receptor signaling pathway. Predicted to localize to photoreceptor outer segment membrane. Is expressed in epiphysis; retinal photoreceptor layer; and retinal rod cell. Human ortholog(s) of this gene implicated in retinitis pigmentosa 57. Orthologous to human PDE6G (phosphodiesterase 6G) and PDE6H (phosphodiesterase 6H).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pde6ga Human Ortholog
No data available
Associated With pde6ga Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR006952 Retinal cGMP phosphodiesterase, gamma subunit
Homologous_superfamily IPR037030 Retinal cGMP phosphodiesterase, gamma subunit superfamily
Domain Details Per Protein
Protein Length Retinal cGMP phosphodiesterase, gamma subunit Retinal cGMP phosphodiesterase, gamma subunit superfamily
UniProtKB:Q502C6 86
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations