Gene

nsmce4a

ID
ZDB-GENE-050522-111
Name
NSE4 homolog A, SMC5-SMC6 complex component
Symbol
nsmce4a Nomenclature History
Previous Names
  • zgc:109897
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to be involved in DNA repair. Predicted to act upstream of or within DNA damage response. Predicted to be located in chromosome, telomeric region. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus. Is expressed in several structures, including alar plate midbrain region; head; immature eye; optic tectum; and pectoral fin bud. Orthologous to several human genes including NSMCE4A (NSE4 homolog A, SMC5-SMC6 complex component).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la012341TgTransgenic insertionUnknownUnknownDNA
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Sequence Targeting Reagents
No data available
Human Disease
Associated With nsmce4a Human Ortholog
No data available
Associated With nsmce4a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR014854 Non-structural maintenance of chromosome element 4, C-terminal
Domain IPR029225 Nse4/EID protein, Nse3/MAGE-binding domain
Family IPR027786 Nse4/EID family
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Domain Details Per Protein
Protein Additional Resources Length Non-structural maintenance of chromosome element 4, C-terminal Nse4/EID family Nse4/EID protein, Nse3/MAGE-binding domain
UniProtKB:A0A8M9QFD5 InterPro 346
UniProtKB:Q504G2 InterPro 346
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 13
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nsmce4a-201 (1) Ensembl 1,352 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-19J14ZFIN Curated Data
EncodescDNAMGC:109897ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanNSMCE4A10
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseNsmce4a7
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
1 - 4 of 4
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