Gene
crygm3
- ID
- ZDB-GENE-050516-6
- Name
- crystallin, gamma M3
- Symbol
- crygm3 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to be a structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Is expressed in lens.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Beta/gamma crystallin | Beta/Gamma-Crystallin | Gamma-crystallin-like |
|---|---|---|---|---|---|
| UniProtKB:Q5XTM9 | InterPro | 174 | |||
| UniProtKB:A0AB32TXW3 | InterPro | 238 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
crygm3-201
(1)
|
Ensembl | 607 nt | ||
| mRNA |
crygm3-202
(1)
|
Ensembl | 1,212 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-212N6 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001007786 (1) | 616 nt | ||
| Genomic | GenBank:CR854911 (1) | 233522 nt | ||
| Polypeptide | UniProtKB:A0AB32TXW3 (1) | 238 aa |
No data available
- Drepanos, L., Gans, I.M., Grendler, J., Guitar, S., Fuqua, J.H., Maki, N.J., Tilden, A.R., Graber, J.H., Coffman, J.A. (2023) Loss of Krüppel-like factor 9 deregulates both physiological gene expression and development. Scientific Reports. 13:1223912239
- Farnsworth, D., Posner, M., Miller, A. (2021) Single cell transcriptomics of the developing zebrafish lens and identification of putative controllers of lens development. Experimental Eye Research. 206:108535
- Takashima, S., Takemoto, S., Toyoshi, K., Ohba, A., Shimozawa, N. (2021) Zebrafish model of human Zellweger syndrome reveals organ-specific accumulation of distinct fatty acid species and widespread gene expression changes. Molecular genetics and metabolism. 133(3):307-323
- Hinaux, H., Blin, M., Fumey, J., Legendre, L., Heuzé, A., Casane, D., Rétaux, S. (2015) Lens defects in Astyanax mexicanus cavefish: evolution of crystallins and a role for alphaA-crystallin. Developmental Neurobiology. 75(5):505-21
- Lin, Y.R., Mok, H.K., Wu, Y.H., Liang, S.S., Hsiao, C.C., Huang, C.H., and Chiou, S.H. (2013) Comparative proteomics analysis of degenerative eye lenses of nocturnal rice eel and catfish as compared to diurnal zebrafish. Molecular Vision. 19:623-637
- Mahler, B., Chen, Y., Ford, J., Thiel, C., Wistow, G., and Wu, Z. (2013) Structure and Dynamics of the Fish Eye Lens Protein, gammaM7-crystallin. Biochemistry. 52(20):3579-87
- Greiling, T.M., Houck, S.A., and Clark, J.I. (2009) The zebrafish lens proteome during development and aging. Molecular Vision. 15:2313-2325
- Posner, M., Hawke, M., Lacava, C., Prince, C.J., Bellanco, N.R., and Corbin, R.W. (2008) A proteome map of the zebrafish (Danio rerio) lens reveals similarities between zebrafish and mammalian crystallin expression. Molecular Vision. 14:806-814
- Vihtelic, T.S., Fadool, J.M., Gao, J., Thornton, K.A., Hyde, D.R., and Wistow, G. (2005) Expressed sequence tag analysis of zebrafish eye tissues for NEIBank. Molecular Vision. 11:1083-1100
- Wistow, G., Wyatt, K., David, L., Gao, C., Bateman, O., Bernstein, S., Tomarev, S., Segovia, L., Slingsby, C., and Vihtelic, T. (2005) gammaN-crystallin and the evolution of the betagamma-crystallin superfamily in vertebrates. The FEBS journal. 272(9):2276-2291
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