ZFIN ID: ZDB-GENE-050513-5
Gene Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Gene Symbol: sema3c    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: si:dkey-105o6.1 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Exhibits neuropilin binding activity. Involved in enteric nervous system development. Predicted to localize to extracellular space and integral component of plasma membrane. Is expressed in caudal tuberculum and otic vesicle. Orthologous to human SEMA3C (semaphorin 3C).
Genome Resources: Alliance (1),  Gene:553130 (1),  Ensembl(GRCz11):ENSDARG00000034300 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015373Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1359 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12671 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15161 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30849 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-sema3c
    1
    CRISPR2-sema3c
    1
    CRISPR3-sema3c
    1
    MO1-sema3c N/A 1
    PHENOTYPE
    Data: Fig. 3 from Jiang et al., 2015
    Observed in:
    DISEASE ASSOCIATED WITH sema3c HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH sema3c VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process enteric nervous system development (more)
    Cellular Component extracellular space (more)
    Molecular Function neuropilin binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sema3c-201 (1)    Ensembl 2141
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sema3c No data available
    MARKER RELATIONSHIPS
    sema3c Contained in: [BAC] DKEY-27K7 (1) (order this), DKEY-105O6 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_017355318 (1)
    Genomic GenBank:BX537168 (1) 200744 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1QGW9 (1) 713 aa
    Sequence Information (all 11)
    ORTHOLOGY for sema3c ( Chr: 4 )
    CITATIONS (32)