Gene

mipepb

ID

ZDB-GENE-050506-64

Name

mitochondrial intermediate peptidase b

Symbol

mipepb Nomenclature History

Previous Names

im:6903007 (1)
si:ch73-1a9.4

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have metalloendopeptidase activity. Predicted to be involved in peptide metabolic process and protein processing involved in protein targeting to mitochondrion. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 31. Orthologous to human MIPEP (mitochondrial intermediate peptidase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6903007 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mipepb Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
combined oxidative phosphorylation deficiency 31	Alliance	Combined oxidative phosphorylation deficiency 31	617228

Associated With mipepb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001567	Peptidase M3A/M3B catalytic domain
Family	IPR033851	Mitochondrial intermediate peptidase
Family	IPR045090	Peptidase M3A/M3B
Homologous_superfamily	IPR024077	Neurolysin/Thimet oligopeptidase, domain 2
Homologous_superfamily	IPR024079	Metallopeptidase, catalytic domain superfamily

Domain Details Per Protein

Protein	Length	Metallopeptidase, catalytic domain superfamily	Mitochondrial intermediate peptidase	Neurolysin/Thimet oligopeptidase, domain 2	Peptidase M3A/M3B	Peptidase M3A/M3B catalytic domain
UniProtKB:A0A2R8QM23 InterPro	655
UniProtKB:F1QIA6 InterPro	680

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	si:ch73-1a9.4-201 (1) Ensembl	Ensembl		2,499 nt	Select Tool ZFIN BLAST
mRNA	si:ch73-1a9.4-202 (1) Ensembl	Ensembl		1,968 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations