Gene
rbp1.1
- ID
- ZDB-GENE-050421-2
- Name
- retinol binding protein 1, cellular, tandem duplicate 1
- Symbol
- rbp1.1 Nomenclature History
- Previous Names
-
- rbp1
- rbp1b (1)
- sb:eu611
- zgc:100825
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable fatty acid binding activity. Predicted to be involved in fatty acid transport. Predicted to be active in cytosol and nucleus. Is expressed in gall bladder and ovary. Human ortholog(s) of this gene implicated in multiple myeloma. Orthologous to human RBP1 (retinol binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu611 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Calycin | Cytosolic fatty-acid binding | Intracellular lipid binding protein | Lipocalin/cytosolic fatty-acid binding domain |
|---|---|---|---|---|---|---|
| UniProtKB:B0R174 | InterPro | 132 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-119O8 | Liu et al., 2005 | |
| Encodes | EST | eu611 | Thisse et al., 2005 | |
| Encodes | cDNA | MGC:100825 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:123123 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:174407 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:193591 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:193620 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_212895 (1) | 968 nt | ||
| Genomic | GenBank:AL953896 (1) | 158018 nt | ||
| Polypeptide | UniProtKB:B0R174 (1) | 132 aa |
- Rozenblat, R., Tovin, A., Zada, D., Lebenthal-Loinger, I., Lerer-Goldshtein, T., Appelbaum, L. (2022) Genetic and Neurological Deficiencies in the Visual System of mct8 Mutant Zebrafish. International Journal of Molecular Sciences. 23(5):
- Alexandre-Moreno, S., Bonet-Fernández, J.M., Atienzar-Aroca, R., Aroca-Aguilar, J.D., Escribano, J. (2021) Null cyp1b1 Activity in Zebrafish Leads to Variable Craniofacial Defects Associated with Altered Expression of Extracellular Matrix and Lipid Metabolism Genes. International Journal of Molecular Sciences. 22(12):
- Takita, S., Seko, Y. (2020) eys+/- ; lrp5+/- Zebrafish Reveals Lrp5 Can Be the Receptor of Retinol in the Visual Cycle. iScience. 23:101762
- Yang, Y.J., Wang, Y., Li, Z., Zhou, L., Gui, J.F. (2017) Sequential, Divergent, and Cooperative Requirements of Foxl2a and Foxl2b in Ovary Development and Maintenance of Zebrafish.. Genetics. 205(4):1551-1572
- Tzung, K.W., Goto, R., Saju, J.M., Sreenivasan, R., Saito, T., Arai, K., Yamaha, E., Hossain, M.S., Calvert, M.E., Orbán, L. (2015) Early Depletion of Primordial Germ Cells in Zebrafish Promotes Testis Formation. Stem Cell Reports. 4(1):61-73
- Sreenivasan, R., Jiang, J., Wang, X., Bartfai, R., Kwan, H.Y., Christoffels, A., and Orban, L. (2014) Gonad Differentiation in Zebrafish Is Regulated by the Canonical Wnt Signaling Pathway. Biology of reproduction. 90(2):45
- Crespo, B., Lan-Chow-Wing, O., Rocha, A., Zanuy, S., Gómez, A. (2013) foxl2 and foxl3 are two ancient paralogs that remain fully functional in teleosts. General and comparative endocrinology. 194:81-93
- Parmar, M.B., Shams, R., and Wright, J.M. (2013) Genomic organization and transcription of the medaka and zebrafish cellular retinol-binding protein (rbp) genes. Marine genomics. 11:1-10
- Chen, L., Hu, C., Huang, C., Wang, Q., Wang, X., Yang, L., and Zhou, B. (2012) Alterations in retinoid status after long-term exposure to PBDEs in zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 120-121C:11-18
- Liu, R.Z., Sun, Q., Thisse, C., Thisse, B., Wright, J.M., and Denovan-Wright, E.M. (2005) The Cellular Retinol-Binding Protein Genes are Duplicated and Differentially Transcribed in the Developing and Adult Zebrafish (Danio rerio). Mol. Biol. Evol.. 22(3):469-477
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