Gene

ccnd2b

ID
ZDB-GENE-050420-354
Name
cyclin D2, b
Symbol
ccnd2b Nomenclature History
Previous Names
  • si:ch211-240j22.2
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in mitotic cell cycle phase transition; positive regulation of G1/S transition of mitotic cell cycle; and regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to localize to cyclin-dependent protein kinase holoenzyme complex; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in ductal carcinoma in situ; invasive lobular carcinoma; prostate cancer; and transitional cell carcinoma. Orthologous to human CCND2 (cyclin D2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Grainger et al., 2016
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ccnd2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 615938
Associated With ccnd2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004367 Cyclin, C-terminal domain
Domain IPR006671 Cyclin, N-terminal
Domain IPR013763 Cyclin-like
Family IPR015451 Cyclin D
Family IPR039361 Cyclin
Homologous_superfamily IPR036915 Cyclin-like superfamily
Domain Details Per Protein
Protein Length Cyclin Cyclin, C-terminal domain Cyclin D Cyclin-like Cyclin-like superfamily Cyclin, N-terminal
UniProtKB:Q1L8M6 295
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations