Gene
dclk2a
- ID
- ZDB-GENE-050420-170
- Name
- doublecortin-like kinase 2a
- Symbol
- dclk2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Enables protein serine/threonine kinase activity. Acts upstream of or within hyperosmotic response and protein autophosphorylation. Located in microtubule cytoskeleton; nucleus; and synaptic vesicle. Is expressed in several structures, including hindbrain neural plate; immature eye; nervous system; optic primordium; and trigeminal placode. Orthologous to human DCLK2 (doublecortin like kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb572 (28 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Shimomura et al., 2007
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR003533 | Doublecortin domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036572 | Doublecortin domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Doublecortin domain | Doublecortin domain superfamily | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AQY6 | InterPro | 801 | ||||||
| UniProtKB:A2A123 | InterPro | 725 | ||||||
| UniProtKB:A2A124 | InterPro | 722 | ||||||
| UniProtKB:A2A121 | InterPro | 810 | ||||||
| UniProtKB:A2A122 | InterPro | 791 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dclk2a-201
(1)
|
Ensembl | 2,294 nt | ||
| mRNA |
dclk2a-202
(1)
|
Ensembl | 4,524 nt | ||
| mRNA |
dclk2a-203
(1)
|
Ensembl | 2,703 nt | ||
| mRNA |
dclk2a-204
(1)
|
Ensembl | 2,642 nt | ||
| mRNA |
dclk2a-205
(1)
|
Ensembl | 2,333 nt | ||
| mRNA |
dclk2a-206
(1)
|
Ensembl | 4,522 nt | ||
| mRNA |
dclk2a-207
(1)
|
Ensembl | 2,490 nt | ||
| mRNA |
dclk2a-208
(1)
|
Ensembl | 2,729 nt | ||
| mRNA |
dclk2a-211
(1)
|
Ensembl | 2,406 nt | ||
| mRNA |
dclk2a-212
(1)
|
Ensembl | 7,324 nt | ||
| mRNA |
dclk2a-213
(1)
|
Ensembl | 2,699 nt | ||
| mRNA |
dclk2a-214
(1)
|
Ensembl | 7,381 nt | ||
| ncRNA |
dclk2a-005
(1)
|
Ensembl | 635 nt | ||
| ncRNA |
dclk2a-006
(1)
|
Ensembl | 486 nt |
Interactions and Pathways
No data available
Plasmids
No data available