Gene
large2
- ID
- ZDB-GENE-050419-253
- Name
- LARGE xylosyl- and glucuronyltransferase 2
- Symbol
- large2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable glucuronosyltransferase activity and xylosyltransferase activity. Predicted to be involved in protein O-linked mannosylation. Predicted to act upstream of or within protein glycosylation. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including brain; lens; mesoderm; pronephros; and shield. Orthologous to human LARGE2 (LARGE xylosyl- and glucuronyltransferase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from Moore et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Moore et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha-1,3-xylosyltransferase/Beta-1,3-glucuronyltransferase | Glycosyl transferase, family 8 | Nucleotide-diphospho-sugar transferases |
|---|---|---|---|---|
|
UniProtKB:Q66PG1
|
750 | |||
|
UniProtKB:B3DFN1
|
750 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
large2-201
(1)
|
Ensembl | 6,919 nt | ||
| mRNA |
large2-202
(1)
|
Ensembl | 2,253 nt | ||
| mRNA |
large2-203
(1)
|
Ensembl | 7,320 nt |
Interactions and Pathways
No data available
Plasmids
No data available