ZFIN is now using GRCz12tu for Genomic Data
Gene

pstpip1a

ID
ZDB-GENE-050419-251
Name
proline-serine-threonine phosphatase interacting protein 1a
Symbol
pstpip1a Nomenclature History
Previous Names
  • si:dkey-24l11.5
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to be involved in several processes, including endocytosis; inflammatory response; and innate immune response. Predicted to be located in several cellular components, including cleavage furrow; lamellipodium; and uropod. Predicted to be active in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in PAPA syndrome and autoinflammatory syndrome with cytopenia, hyperzincemia, and hypercalprotectinemia. Orthologous to human PSTPIP1 (proline-serine-threonine phosphatase interacting protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pstpip1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autoinflammatory syndrome with cytopenia, hyperzincemia, and hypercalprotectinemia Alliance Autoinflammatory syndrome with cytopenia, hyperzincemia, and hypercalprotectinemia 601979
PAPA syndrome Alliance Pyogenic sterile arthritis, pyoderma gangrenosum, and acne 604416
Associated With pstpip1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001060 FCH domain
Domain IPR001452 SH3 domain
Domain IPR030777 PSTPIP1, SH3 domain
Domain IPR031160 F-BAR domain
Homologous_superfamily IPR027267 AH/BAR domain superfamily
Homologous_superfamily IPR036028 SH3-like domain superfamily
Domain Details Per Protein
Protein Additional Resources Length AH/BAR domain superfamily F-BAR domain FCH domain PSTPIP1, SH3 domain SH3 domain SH3-like domain superfamily
UniProtKB:Q1LX61 InterPro 418
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pstpip1a-201 (1)
Ensembl
Ensembl 1,262 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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