Gene

capn12

ID
ZDB-GENE-050419-245
Name
calpain 12
Symbol
capn12 Nomenclature History
Previous Names
  • si:ch211-160d20.1
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity and calcium-dependent cysteine-type endopeptidase activity. Involved in keratinocyte differentiation. Predicted to localize to cytoplasm. Orthologous to human CAPN12 (calpain 12).
Genome Resources
Note
None
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. 4 from Bochner et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With capn12 Human Ortholog
No data available
Associated With capn12 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR000169 Cysteine peptidase, cysteine active site
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Domain IPR001300 Peptidase C2, calpain, catalytic domain
Domain IPR002048 EF-hand domain
Domain IPR022682 Peptidase C2, calpain, large subunit, domain III
Domain IPR022683 Peptidase C2, calpain, domain III
Domain IPR033883 Calpain subdomain III
Family IPR022684 Peptidase C2, calpain family
Homologous_superfamily IPR011992 EF-hand domain pair
Homologous_superfamily IPR036213 Calpain large subunit, domain III superfamily
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length Calpain large subunit, domain III superfamily Calpain subdomain III Cysteine peptidase, cysteine active site EF-Hand 1, calcium-binding site EF-hand domain EF-hand domain pair Papain-like cysteine peptidase superfamily Peptidase C2, calpain, catalytic domain Peptidase C2, calpain, domain III Peptidase C2, calpain family Peptidase C2, calpain, large subunit, domain III
UniProtKB:A0A286Y9R3 666
UniProtKB:A0A2R8QQX3 637
UniProtKB:F1QL66 713
UniProtKB:Q1LUX4 685
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations