lrguk

ID

ZDB-GENE-050419-232

Name

leucine-rich repeats and guanylate kinase domain containing

Symbol

lrguk Nomenclature History

Previous Names

si:ch211-234m22.1

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable ATP binding activity and kinase activity. Predicted to be located in acrosomal vesicle. Orthologous to human LRGUK (leucine rich repeats and guanylate kinase domain containing).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lrguk Human Ortholog

No data available

Associated With lrguk Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR008144	Guanylate kinase-like domain
Domain	IPR008145	Guanylate kinase/L-type calcium channel beta subunit
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Repeat	IPR001611	Leucine-rich repeat

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M3B1R3	InterPro	726
UniProtKB:A0A8M9PHU2	InterPro	739
UniProtKB:Q1L8G4	InterPro	730
UniProtKB:A0AB32TU23	InterPro	739
UniProtKB:A0AB32TVG2	InterPro	726
UniProtKB:A0AC58J9Q2	InterPro	739
UniProtKB:A0AC58J9Q8	InterPro	739
UniProtKB:A0AC58J9S2	InterPro	717
UniProtKB:A0AC58J9T7	InterPro	726