ZFIN is now using GRCz12tu for Genomic Data
Gene
si:ch211-260p9.3
- ID
- ZDB-GENE-050419-185
- Name
- si:ch211-260p9.3
- Symbol
- si:ch211-260p9.3 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Human ortholog(s) of this gene implicated in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. Orthologous to human PLCG2 (phospholipase C gamma 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000008 | C2 domain |
| Domain | IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain |
| Domain | IPR000980 | SH2 domain |
| Domain | IPR001711 | Phospholipase C, phosphatidylinositol-specific, Y domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR035024 | PLC-gamma, N-terminal SH2 domain |
| Domain | IPR057061 | PLCG, EF-hand domain 2 |
| Family | IPR001192 | Phosphoinositide phospholipase C family |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR017946 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR036860 | SH2 domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C2 domain | C2 domain superfamily | EF-hand domain pair | PH-like domain superfamily | Phosphatidylinositol-specific phospholipase C, X domain | Phosphoinositide phospholipase C family | Phospholipase C, phosphatidylinositol-specific, Y domain | PLC-gamma, N-terminal SH2 domain | PLCG, EF-hand domain 2 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily | Pleckstrin homology domain | SH2 domain | SH2 domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB32TDQ0 | InterPro | 1135 | |||||||||||||
| UniProtKB:A0AC58HVI4 | InterPro | 1061 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-260p9.3-201
(1)
|
Ensembl | 812 nt | ||
| mRNA |
si:ch211-260p9.3-202
(1)
|
Ensembl | 1,426 nt | ||
| mRNA |
si:ch211-260p9.3-203
(1)
|
Ensembl | 810 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers