Gene
iqcg
- ID
- ZDB-GENE-050419-109
- Name
- IQ motif containing G
- Symbol
- iqcg Nomenclature History
- Previous Names
-
- iqcg (1)
- si:ch211-222m18.3
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable calmodulin binding activity. Acts upstream of or within definitive hemopoiesis. Located in motile cilium. Is expressed in blastomere; brain; and pleuroperitoneal region. Orthologous to human IQCG (IQ motif containing G).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chen et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa9928 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa25066 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa39202 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa39203 | Allele with one point mutation | Unknown | Premature Stop | ENU |
1 - 4 of 4
Show
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| MO1-iqcg | N/A | Chen et al., 2014 |
| MO2-iqcg | N/A | Chen et al., 2014 |
| MO3-iqcg | N/A | Choksi et al., 2014 |
1 - 3 of 3
Show
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Dynein regulatory complex protein 9 | IQ motif, EF-hand binding site |
|---|---|---|---|---|
| UniProtKB:A0A8M1RMF7 | InterPro | 345 | ||
| UniProtKB:A3KQH2 | InterPro | 346 |
1 - 2 of 2
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-222M18 | ZFIN Curated Data |
1 - 1 of 1
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001346240 (1) | |||
| Genomic | GenBank:BX649600 (1) | 228633 nt | ||
| Polypeptide | UniProtKB:A3KQH2 (1) | 346 aa |
- Comparative Orthology
- Alliance
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Chen, L.T., Liang, W.X., Chen, S., Li, R.K., Tan, J.L., Xu, P.F., Luo, L.F., Wang, L., Yu, S.H., Meng, G., Li, K.K., Liu, T.X., Chen, Z., Chen, S.J. (2014) Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish. Nature communications. 5:3811
- Choksi, S.P., Babu, D., Lau, D., Yu, X., Roy, S. (2014) Systematic discovery of novel ciliary genes through functional genomics in the zebrafish. Development (Cambridge, England). 141:3410-9
1 - 3 of 3
Show