Gene

dmbx1b

ID
ZDB-GENE-050417-97
Name
diencephalon/mesencephalon homeobox 1b
Symbol
dmbx1b Nomenclature History
Previous Names
  • mbx2 (1)
  • zgc:112395
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have sequence-specific DNA binding activity. Involved in several processes, including nervous system development; regulation of neural retina development; and retina development in camera-type eye. Predicted to localize to nucleus. Is expressed in midbrain neural keel; midbrain neural rod; nervous system; and trigeminal placode. Orthologous to human DMBX1 (diencephalon/mesencephalon homeobox 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Wong et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dmbx1b Human Ortholog
No data available
Associated With dmbx1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR003654 OAR domain
Family IPR052488 Diencephalon/mesencephalon homeobox
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Diencephalon/mesencephalon homeobox Homedomain-like superfamily Homeobox, conserved site Homeodomain OAR domain
UniProtKB:Q566X8 369
UniProtKB:B2GPS4 369
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA dmbx1b-201 (1) Ensembl 1,430 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations