Gene
atg16l1
- ID
- ZDB-GENE-050417-401
- Name
- ATG16 autophagy related 16-like 1 (S. cerevisiae)
- Symbol
- atg16l1 Nomenclature History
- Previous Names
-
- fb57e05
- wu:fb57e05
- zgc:110147
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable protein-membrane adaptor activity. Predicted to be involved in autophagosome assembly. Predicted to be part of Atg12-Atg5-Atg16 complex. Predicted to be active in autophagosome membrane and phagophore assembly site membrane. Is expressed in intestine. Human ortholog(s) of this gene implicated in inflammatory bowel disease 10. Orthologous to human ATG16L1 (autophagy related 16 like 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110147 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| inflammatory bowel disease 10 | Alliance | {Inflammatory bowel disease (Crohn disease) 10} | 611081 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR013923 | Autophagy-related protein 16 domain |
| Family | IPR045160 | Autophagy-related protein 16 |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | Autophagy-related protein 16 | Autophagy-related protein 16 domain | G-protein beta WD-40 repeat | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q568R2 | InterPro | 330 | |||||||
| UniProtKB:A0A8M1N5D3 | InterPro | 606 | |||||||
| UniProtKB:A0AB32T1C2 | InterPro | 621 | |||||||
| UniProtKB:A0AB32T1D2 | InterPro | 620 | |||||||
| UniProtKB:A0AB32T429 | InterPro | 605 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
atg16l1-201
(1)
|
Ensembl | 1,866 nt | ||
| mRNA |
atg16l1-202
(1)
|
Ensembl | 4,727 nt | ||
| mRNA |
atg16l1-203
(1)
|
Ensembl | 699 nt | ||
| mRNA |
atg16l1-204
(1)
|
Ensembl | 990 nt |
Interactions and Pathways
No data available
Plasmids
No data available