Gene
arl3a
- ID
- ZDB-GENE-050417-368
- Name
- ADP ribosylation factor like GTPase 3a
- Symbol
- arl3a Nomenclature History
- Previous Names
-
- si:dkey-52k1.1
- zgc:110197
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity. Predicted to be involved in cilium assembly. Predicted to be active in cytoplasm and microtubule cytoskeleton. Is expressed in neural tube; otic placode; and pronephric duct. Human ortholog(s) of this gene implicated in Joubert syndrome and retinitis pigmentosa 83. Orthologous to human ARL3 (ADP ribosylation factor like GTPase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110197 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 83 | Alliance | Retinitis pigmentosa 83 | 618173 |
| Joubert syndrome 35 | 618161 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ADP-ribosylation factor-like protein 2/3 | P-loop containing nucleoside triphosphate hydrolase | Small GTPase superfamily, ARF/SAR type | Small GTP-binding domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A2R8QI61
|
182 | ||||
|
UniProtKB:Q568N2
|
96 |
Interactions and Pathways
No data available
Plasmids
No data available