Gene

zgc:110319

ID

ZDB-GENE-050417-345

Name

zgc:110319

Symbol

zgc:110319 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have 4 iron, 4 sulfur cluster binding activity and iron ion binding activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation by iron-sulfur cluster transfer. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 1. Orthologous to human NFU1 (NFU1 iron-sulfur cluster scaffold).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:110319 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With zgc:110319 Human Ortholog

No data available

Associated With zgc:110319 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001075	NIF system FeS cluster assembly, NifU, C-terminal
Domain	IPR014824	Scaffold protein Nfu/NifU, N-terminal
Family	IPR035433	NFU1-like
Homologous_superfamily	IPR034904	Fe-S cluster assembly domain superfamily
Homologous_superfamily	IPR036498	Scaffold protein Nfu/NifU, N-terminal domain superfamily

Domain Details Per Protein

Protein	Length	Fe-S cluster assembly domain superfamily	NFU1-like	NIF system FeS cluster assembly, NifU, C-terminal	Scaffold protein Nfu/NifU, N-terminal	Scaffold protein Nfu/NifU, N-terminal domain superfamily
UniProtKB:B8A6A3 InterPro	256
UniProtKB:Q6P002 InterPro	255

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	zgc:110319-201 (1) Ensembl	Ensembl	1,554 nt	Select Tool ZFIN BLAST
mRNA	zgc:110319-203 (1) Ensembl	Ensembl	944 nt	Select Tool ZFIN BLAST
mRNA	zgc:110319-207 (1) Ensembl	Ensembl	357 nt	Select Tool ZFIN BLAST
ncRNA	zgc:110319-002 (1) Ensembl	Ensembl	755 nt	Select Tool ZFIN BLAST
ncRNA	zgc:110319-003 (1) Ensembl	Ensembl	768 nt	Select Tool ZFIN BLAST
ncRNA	zgc:110319-004 (1) Ensembl	Ensembl	773 nt	Select Tool ZFIN BLAST
ncRNA	zgc:110319-006 (1) Ensembl	Ensembl	608 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations