nsmaf

ID

ZDB-GENE-050417-342

Name

neutral sphingomyelinase (N-SMase) activation associated factor

Symbol

nsmaf Nomenclature History

Previous Names

FAN (1)
zgc:111982

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Acts upstream of or within leukocyte chemotaxis involved in immune response; leukocyte chemotaxis involved in inflammatory response; and neutrophil chemotaxis. Orthologous to human NSMAF (neutral sphingomyelinase activation associated factor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:111982 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Boecke et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nsmaf Human Ortholog

No data available

Associated With nsmaf Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000409	BEACH domain
Domain	IPR004182	GRAM domain
Domain	IPR023362	PH-BEACH domain
Family	IPR050865	BEACH Domain-Containing
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Homologous_superfamily	IPR036372	BEACH domain superfamily
Repeat	IPR001680	WD40 repeat